Bio-nano interface

Even though they are less known than other nanosystems, iron-carbohydrate nanocomplexes for parenteral administration were the first nanomedicines introduced to the market - as early as 1948, long before nanotechnology was recognized as a scientific discipline.

The BINAS project aims to unravel how iron-carbohydrate nanoparticles interact with biomolecules once they enter the bloodstream, and how these interactions influence cellular responses. Particular attention is given to the role of the carbohydrate shell, as well as the size and shape of the nanocomplexes, to better understand their biological behavior in the context of clinical applications.

These insights will help to clarify the complex interplay occurring in the human body and provide translatable methodologies for studying other nanomedicines.