Analytics

Drugs in formulations and in drug delivery experiments need to be quantified by specific, sensitive and robust analytical arsenal:


> HPLC-UV-Fluo and HPLC-Ion chromatography

High pressure liquid chromatography ensures accurate and precise quantification of lipophilic and polar, neutral and ionized drugs in formulation and in vitro experiment samples: the typical limits of quantification are of 5 μg/ml.

Chromatic separation and identification of TRN isomers

> UHPLC-UV

Ultra High pressure liquid chromatography ensures accurate and precise quantification of lipophilic and polar, neutral and ionized drugs in formulation and in vitro experiment samples: the typical limits of quantification are of 5 μg/ml. Moreover the chromatographic system is miniaturized leading to short analysis times and thus high throughput analyses.

UPLC-MS/MS

> UHPLC-MS/MS

UHPLC-MS/MS combines the advantages of UHPLC and the cutting edge tandem mass detection with the ability to detect the analytes selectively in complex matrixes and with ultra-high sensitivity: : the typical limits of quantification are of 5 ng/ml.

MRM scan of testosterone

> Flash chromatography

Flash chromatography is a preparative HPLC system used to purifiy reaction mixtures during the prodrug synthesis activities.

> Immunoassays

Proteic drugs that cannot undergo chromatography are often quantified using immunoassay provided as kits or developed in house.