Improving drug bioavailability in the anterior and posterior segments¶
A new research activity concerns investigation into methods to improve drug delivery to the eye.
Particular emphasis has been on the combination of short duration ocular iontophoresis with prodrug conjugates possessing physicochemical properties that favour their electrotransport into the eye.
We are interested in both corneal iontophoresis and transscleral iontophoresis, which enables the posterior segment to be reached.
Again, a new experimental set-up, involving use of the whole eye globe, enables evaluation of drug bioavailability in the different ocular compartments.