Nanos for ocular AMD

Retinal pathologies are diseases affecting the posterior segment of the eye, an area that is difficult to access for treatment. Intravitreal injection is the main route of administration, because it directly targets the area of interest. However, this highly invasive administration has rare but serious side effects and is a heavy burden for the patient, who often stops the treatment early. It is therefore essential to look at other less invasive ocular delivery routes. This project focuses on the development of different nanoparticles and polymeric solutions for topical application (eye drops). The selected raw materials, by promoting ocular absorption, increasing the residence time at the surface of the eye and solubilizing more API, allow to optimize ocular bioavailability and to reach the retina.