2022¶

• Synthesis, Formulation and Characterization of Immunotherapeutic Glycosylated Dendrimer/cGAMP Complexes for CD206 Targeted Delivery to M2 Macrophages in Cold Tumors

  Petrovic, M.; Porcello, A.; Tankov, S.; Majchrzak, O.B.; Kiening, M.; Laingoniaina, A.C.; Jbilou, T.; Walker, P.R.; Borchard, G.; Jordan, O.
  Pharmaceutics 14 (2022), 1883 10.3390/pharmaceutics14091883

• Polyethylenimine/cGAMP Nanocomplexes for STING-Mediated Cancer Immunotherapy: Formulation and Characterization Using Orthogonal Techniques

  Petrovic, M.; Borchard, G.; Jordan, O.
  Processes 2022 10(5) 882 10.3390/pr10050882

• Synergistic effects of anitimicrobial peptide dendrimer-chitosan polymer conjugates against Pseudomonas aeruginosa

  Patrulea, V.; Gan, B.-H.; Perron, K.; Cai, X.; Abdel-Sayed, P.; Sublet, E.; Ducret, V.; Porroche Nerhot, N.; Applegate, L. A.; Borchard, G.; Reymond, J.-L.; Jordan, O.
  Carbohydrate Polymers 280 (2022), 119025 10.1016/j.carbpol.2021.119025

• Structure-activity relationship of a peptide permeation enhancer

  Brunner, J.; Borchard, G.
  Tissue Barriers 2022. 10.1080/21688370.2022.2060692

• Impact of peptide permeation enhancer on tight junctions opening cellular mechanisms

  Brunner, J.; Schvartz, D.; Gouiller, A.; Hainard, A.; Borchard, G.
  Biochem. Biophys. Rep. (2022) 27;32: 101375 10.1016/j.bbrep.2022.101375

• A New Practice to Monitor the Fabrication Process of Fab-Targeting Ligands from Bevacizumab by LC-MS: Preparation and Analytical Characterization

  Marquet, F.; D’Atri V.; Guillarme, D.; Borchard, G.
  Sci Pharm 2022, 90 (1) 5 10.3390/scipharm90010005

• Characterization of the Interaction of Polymeric Micelles with siRNA: A Combined Experimental and Molecular Dynamics Study

  Marquet, F.; Stojceski, F.; Grasso, G.; Patrulea, V.; Danani, A.; Borchard, G.
  Polymers 14 (2022) 44096 10.3390/polym14204409

• Characterization Challenges of Self-Assembled Polymer-SPIONs Nanoparticles: Benefits of Orthogonal Methods

  Marques, C.; Maurizi, L.; Borchard, G.; Jordan, O.
  Int J Mol Sci 2022, 23 (24) 16124 10.3390/ijms232416124

• Translating a Thin-Film Rehydration Method to Microfluidics for the Preparation of a SARS-CoV-2 DNA Vaccine: When Manufacturing Method Matters.

  Peletta, A., Prompetchara, E., Tharakhet, K., Kaewpang, P., Buranapraditkun, S., Yostreerat, N.; Manopwisedjaroen, S.; Thitithanyanont-, A.; Avaro, J.; Krupnik, L.; Neels, A.; Ruxrungtham, K.; Ketloy, C.; Borchard, G.
  Pharmaceutics 2022, 14(7), 1427 10.3390/pharmaceutics14071427

• Need for Expansion of Pharmacy Education Globally for the Growing Field of Nanomedicine

  Barton, A.E.; Borchard, G.; Wacker, M.G.; Pastorin, G.; Saleem, I.Y.; Chaudary, S.; Elbayoumi, T.; Zhaho, Z.; Flühmann, B. A
  Pharmacy 10 (2022) 17 10.3390/pharmacy10010017

• Regulatory safety evaluation of nanomedical products: key issues to refine

  De Jong, W.H.; Geertsma, R.E.; Borchard, G.
  Drug Deli, Translat. Res. 12 (2022) 2042-2047 10.1007/s13346-022-01208-4

• Bioadhesive Hyaluronic Acid/Dopamine Hydrogels for Vascular Applications Prepared by Initiator-Free Crosslinking

  Melnik, T., Ben Ameur, S.; Kanfar, N.; Vinet, L.; Delie Salmon, F.; Jordan, O.
  Int J Mol Sci 2022, 23, (10), 5706 10.3390/ijms23105706

• Bioadhesive Perivascular Microparticle-Gel Drug Delivery System for Intimal Hyperplasia Prevention: In Vitro Evaluation and Preliminary Biocompatibility Assessment

  Melnik, T.; Porcello, A.; Saucy, F.; Delie Salmon, F.; Jordan, O.
  Gels 2022, 8(12), 776 10.3390/gels8120776

• Pharmacological prevention of intimal hyperplasia: A state-of-the-art review

  Melnik, T.; Jordan, O.; Corpataux, J.-M.; Delie Salmon, F.; Saucy, F.
  Pharmacol & Ther. 235:108157 (2022) 10.1016/j.pharmthera.2022.108157

• Combination of mesenchymal stem cells and bioactive molecules in hydrogels for osteoarthritis treatment

  Gonzalez Fernandez, P.; Rodriguez-Nogales, C.; Jordan, O.; Allémann, E.
  Eur J Pharm Biopharm. 2022 Mar; 172:41-52 10.1016/j.ejpb.2022.01.003

• Nanoforming Hyaluronan Based Thermoresponsive Hydrogels: Optimized and Tunable Functionality in Osteoarthritis Management

  Porcello, A.; Gonzalez Fernandez, P.; Jordan, O.; Allémann, E.
  Pharmaceutics (2022), 14(3), 659 10.3390/pharmaceutics14030659

2021¶

• Osteoarthritis in vitro models: Applications and Implications in Development of Intra-Articular Drug Delivery Systems

  Salgado, C.; Jordan, O.; Allémann, E.
  Pharmaceutics 13:60 (2021) 10.3390/pharmaceutics13010060

• Combination of Hyaluronan and Lyophilized Progenitor Cell Derivatives: Stabilization of Functional Hydrogel Products for Therapeutic Management of Tendinous Tissue Disorders

  Laurent, A.; Porcello, A.; Fernandez, P.G.; Jeannerat, A.; Peneveyre, C.; Abdel-Sayed, P.; Scarletta, C.; Hirt-Burri, N.; Michetti, M.; de Buys Roessingh, A.; Raffoul, W.; Allémann, E.; Jordan, O.; Applegate, L.A.
  Pharmaceutics 13 :2196 (2021). 10.3390/pharmaceutics13122196

• Synergistic effects of antimicrobial peptide dendrimer-chitosan polymer conjugates against Pseudomonas aeruginosa

  Patrulea, V.; Gan, B.H.; Perron, K.; Cai, X.; Abdel-Sayed, P.; Sublet, E.; Ducret, V.; Porroche Nerhot, N.; Applegate, L.A.; Borchard, G.; Reymond, J.L.; Jordan, O.
  Carbohydrate Polymers 280:119025 (2021) 10.1016/j.carbpol.2021.119025

• Wound healing promotion by hyaluronic acid: effect of molecular weight on gene expression and in vivo wound closure

  Kawano, Y.; Patrulea, V.; Jordan, O.; Borchard, G.; Lyoda, T.; Kageyama, R.; Morita, A.; Seino, S.; Yoshida H.; Hanawa, T.
  Pharmaceuticals 2021, 14, 301 10.3390/ph14040301

• Better pandemic influenza preparedness through adjuvant technology transfer; challenges and lessons learned

  Lemoine, C.H.; Nidom, R.V.; Ventura, R.; Indrasari, S.; Normalina, I.; Santoso, K.P.; Derouet, F.; Barnier-Quer, C.; Collin, N.; Borchard, G.; Nidom, C.A.
  Vaccines (Basel) 2021, 9, 461 10.3390/vaccines9050461

• A science-based, pragmatic regulatory approach for complex generics through 505(j) or 505(b)(2) pathways

  Klein, K.; Borchard, G.; Shah, V.P.; Flühmann, B.; McNeil, S.E.; de Vlieger, J.S.B.
  Ann. N.Y. Acad. Sci. 2021, 1502, 5-13 10.1111/nyas.14662

• Comparison of triblock copolymeric micelles based on α- and ε-poly(L-Lysine): A Cornelian Choice

  Marquet, F.; Patrulea, V.; Borchard, G.
  Polymer J. 2021, 54, 199-209 10.1038/s41428-021-00552-5

• Considerations for the delivery of STING ligands in cancer immunotherapy

  Petrovic, M.; Borchard, G.; Jordan, O.
  J Control Release. 2021 339 235-247 10.1016/j.jconrel.2021.09.033

• Toward a more equitable SARS-CoV-2 vaccine distribution: a cationic liposome formulation enhances the immunogenicity of a SARS-CoV-2 DNA vaccine candidate

  Peletta, A.; Prompetchara, E.; Tharakhet, K.; Kaewpang, P.; Buranapraditkun, S.; Techawiwattanaboon, T.; Jbilou, T.; Krangvichian, P.; Sirivichayakul, S.; Manopwisedjaroen, S.; Thitithanyanont, A.; Patarakul, K.; Ruxrungtham, K.; Ketloy, C.; Borchard, G.
  Vaccines (Basel) 2021, 9, 874 10.3390/vaccines 9080874

• Target specific tight junction modulators, Advanced Drug Delivery

  Brunner, J.; Ragupathy, S.; Borchard, G.
  Advanced Drug Delivery Reviews 2021 10.1016/j.addr.2021.02.008

• Short peptide sequence enhances epithelial permeability through interaction with protein kinase C

  Ragupathy, S.; Brunner, J.; Borchard, G.
  European Journal of Pharmaceutical Sciences 2021 10.5747/j.ejps.2021.105747

2020¶

• Polymeric nano-biomaterials for medical applications: advancements in developing and implementation considering safety-by-Design concepts

  Borchard, G., Som, C., Zinn, M., Ostafe, V., Borges, O., Perale, G. and Wick, P.
  Front. Bioengin. Biotechnol. (2020) 10.3389/fbioe.2020.599950

• An Update on Antimicrobial Peptides (AMPs) and Their Delivery Strategies for Wound Infections

  Patrulea, V., Borchard, G. and Jordan, O.
  Pharmaceutics 12(9):840 10.3390/pharmaceutics12090840

• Nano wet milled celecoxib extended release microparticles for local management of chronic inflammation

  Jordan, O., Salgado, C., Guénée, L., Černý, R. and Allémann, E.
  Int J Pharm 589:119783 (2020) 10.1016/j.ijpharm.2020.119783

• A Methodological Safe-by-Design Approach for the Development of Nanomedicines

  Schmutz, M., Borges, O., Jesus, S., Borchard, G., Perale, G., Zinn, M., Sips, A.J.A.M., Soeteman-Hernández, L.G., Wick, P. and Som, C.
  Front. Bioengin. Biotechnol. 8 10.3389/fbioe.2020.00258

• Are Antimicrobial Peptide Dendrimers an Escape from ESKAPE?

  Kawano, Y., Jordan, O., Hanawa, T., Borchard, G. and Patrulea, V.
  Advances in wound care 10.1089/wound.2019.1113

• How the Lack of Chitosan Characterization Precludes Implementation of the Safe-by-Design Concept

  Marques, C., Som, C., Schmutz, M., Borges, O. and Borchard, G.
  Front. Bioengin. Biotechnol. 8:165 10.3389/fbioe.2020.00165

• Factors Influencing Safety and Efficacy of Intravenous Iron-Carbohydrate Nanomedicines: From Production to Clinical Practice

  Nikravesh, N., Borchard, G., Hofmann, H., Philipp, E., Flühmann, B. and Wick, P.
  Nanomedicine: nanotechnology, biology, and medicine 26:102178 10.1016/j.nano.2020.102178

• Ethanolic extract of Tunisian propolis: chemical composition, antioxidant, antimicrobial and antiproliferative properties

  Béji-Srairi, R., Younes, I., Mejd, S., Yahyaoui, K., Borchard, g., Riadh, K., Frachel, V. and Ksouri Wided, M.
  Journal of Apicultural Research 10.1080/00218839.2020.1732572

• Chitosan Nanoparticles: Shedding Light on Immunotoxicity and Hemocompatibility

  Jesus, S., Marques A.P., Duarte, A., Soares, E., Panaõ Costa, J., Colaço, M., Schmutz, M., Som, C., Borchard, G., Wick, P. and Borges, O.
  Front. Bioeng. Biotechnol. 8:100 10.3389/fbioe.2020.00100

• Nanomedicines: Addressing the Scientific and Regulatory Gap

  Tinkle, S., McNeil, S. E., Muhlebach, S., Bawa, R., Borchard, G., Barenholz, Y. C., Tamarkin, L. and Desai, N.
  Ann N Y Acad Sci. 2014 1313 35-56 10.1111/nyas.12403

• Guidelines as a starting point to address the needs of small and medium enterprises regarding the Safe-by-Design of polymeric nanobiomaterials for drug delivery

  Schmutz, M., Borges, O., Borchard, G., Wick, P. and Som, C.
  Nanomaterials for Theranostics and Tissue Engineering 10.1016/B978-0-12-817838-6.00010-3

• Chitosan-based systems for controlled delivery of antimicrobial peptides for biomedical application

  Patrulea, V., Younes, I., Jordan, O. and Borchard, O.
  Functional Chitosan 10.1007/978-981-15-0263-7

2019¶

• Differences between intravenous iron products: focus on treatment of iron deficency in chronic heart failure patients

  Martin-Malo, A., Borchard, G., Flühmann, B., Mori, C., Silverberg, D. and Jankowska, E. A.
  ESC Heart Failure 10.1002/ehf2.12400

• Nanomedicines in clinical practice: Are colloidal iron sucrose ready-to-use intravenous solutions interchangeable?

  Di Francesco, T., Sublet, E. and Borchard, G.
  Eur J Pharm Sci. 2019 69-74 10.1016/j.ejps.2019.02.012

• Evaluation of cellulose nanocrystal addition on morphology, compression modulus and cytotoxicity of poly (3-hydroxybutyrate-co-3-hydroxyvalerate) scaffolds

  do Amaral Montanheiro, T. L., Stieven Montagna, L., Patrulea, V., Jordan, O., Borchard, G., Metheus Monteiro Lobato, G., Catalani, L. H. and Lemes, A. P.
  J. Mater Sci (2019) 54: 7198 10.1007/s10853-019-03398-8

• Nanomedicines: The magic bullets reaching their target?

  Flühmann, B., Ntai, I., Borchard, G., Simoens, S., and Mühlebach, S.
  Eur J Pharm Sci. 2019 73-80 10.1016/j.ejps.2018.11.019

• Iron polymaltose complexes: could we spot physicochemical differences in medicines sharing the same active substance?

  Di Francesco, T., Delafontaine, L., Philipp E. and Borchard, G.
  Eur. J. Pharm. Sci. (2019) 10.1016/j.ejps.2019

• Molecular modeling for nanomaterials toxicology: opportunities, challenges and perspectives

  Casalini, T., Limongelli, V., Schmutz, M., Som, C., Jordan,O., Wick, P., Borchard, G. and Perale, G.
  Frontiers Bioengin. (2019) 10.3389/fbioe.2019.00268

• Hazard assessment of polymeric nanobiomaterials for drug delivery: what can we learn from literature so far

  Jesus, S., Schmutz, M., Som, C., Borchard, G., Wick, P. and Borges, O.
  Frontiers Bioengin. (2019) 10.3389/fbioe.2019.00261

• Impact of covalently Nile Red and covalently Rhodamine labeled fluorescent polymer micelles for the improved imaging of the respective drug delivery system

  Trubitsyn, G., Nguyen, V.N., Di Tommaso, C., Borchard, G., Gurny, R. and Möller, M.
  Eur. J. Pharm. Biopharm. 142 (2019) 480-487 10.1016/j.ejpb.2019.07.020

• Bridging communities in the field of nanomedicine

  Halamoda-Kenzaouia, B., Baconnier, S., Bastogne, T., Bazile, D., Boisseau, P., Borchard, G., Even Borgos, S., Calzolai, L., Cederbrant, K., Di Felice,G., Di Francesco, T., Dobrovolskaia, M.A., Gaspar, R., Gracia, B., Hackley, V.A., Leyens, L., Liptrott, N., Park, M. and Patri, A., Roebben, G., Roesslein, M., Thürmer, R., Urbán, P., Zuanga, V. Bremer-Hoffmann, S.
  Regul. Toxicol. Pharmacol. 106 (2019) 187-196 10.1016/j.yrtph.2019.04.011

• Enhanced water uptake of PHBV scaffolds with functionalized cellulose nanocrystals

  do Amaral Montanheiro, T.L., Montagna, L.S., Patrulea, V., Jordan, O., Borchard, G., Ribas, R.G., Bastos Campos, T.M., Thim, G.P. and Lemes A.P.
  Polymer testing 79 : 106079 (2019 10.1016/j.polymertesting.2019.106079

• Polyelectrolyte nanocomplexes based on chitosan derivatives for wound healing application

  Patrulea, V., Applegate, L.A., Ostafe, V., Borchard, G. and Jordan, O.
  European Eur. J. Pharm. Biopharm 140:100-108 (2019) 10.1016/j.ejpb.2019.05.009

2018¶

• antimicrobial and proapoptotic activity against bladder cancer cells

  Varan, G., Patrulea, V., Borchard, G. and Bilensoy, E.
  Nanomaterials (Basel). 2018 8 2 10.3390/nano8020067

• Design and characterization of a perivascular PLGA coated PET mesh sustaining the release of atorvastatin for the prevention of intimal hyperplasia

  Mylonaki, I., Trosi, O., Allemann, E., Durand, M., Jordan, O. and Delie, F.
  Int J Pharm. 2018 537 1-2 40-47 10.1016/j.ijpharm.2017.12.026

• Imaging the porous structure in the core of degrading PLGA microparticles: The effect of molecular weight

  Mylonaki, I., Allemann, E., Delie, F. and Jordan, O.
  J Control Release. 2018 286 231-239 10.1016/j.jconrel.2018.07.044

• Evaluating intimal hyperplasia under clinical conditions

  Mylonaki, I., Allain, E., Strano, F., Allemann, E., Corpataux, J. M., Meda, P., Jordan, O., Delie, F., Rougemont, A. L., Haefliger, J. A. and Saucy, F.
  Interact Cardiovasc Thorac Surg. 2018 27 3 427-436 10.1093/icvts/ivy101

• Nanocrystal-Polymer Particles: Extended Delivery Carriers for Osteoarthritis Treatment

  Maudens, P., Seemayer, C. A., Thauvin, C., Gabay, C., Jordan, O. and Allemann, E.
  Small. 2018 14 8 10.1002/smll.201703108

• Nanocrystals of a potent p38 MAPK inhibitor embedded in microparticles: Therapeutic effects in inflammatory and mechanistic murine models of osteoarthritis

  Maudens, P., Seemayer, C. A., Pfefferle, F., Jordan, O. and Allemann, E.
  J Control Release. 2018 276 102-112 10.1016/j.jconrel.2018.03.007

• Self-assembled thermoresponsive nanostructures of hyaluronic acid conjugates for osteoarthritis therapy

  Maudens, P., Meyer, S., Seemayer, C. A., Jordan, O. and Allemann, E.
  Nanoscale. 2018 10 4 1845-1854 10.1039/c7nr07614b

• Recent advances in intra-articular drug delivery systems for osteoarthritis therapy

  Maudens, P., Jordan, O. and Allemann, E.
  Drug Discov Today. 2018 10.1016/j.drudis.2018.05.023

• Adjuvant Activity of Poly-epsilon-caprolactone/Chitosan Nanoparticles Characterized by Mast Cell Activation and IFN-gamma and IL-17 Production

  Jesus, S., Soares, E., Borchard, G. and Borges, O.
  Mol Pharm. 2018 15 1 72-82 10.1021/acs.molpharmaceut.7b00730

• Hydrogels in three-dimensional dendritic cell (MUTZ-3) culture as a scaffold to mimic human immuno competent subcutaneous tissue

  Groell, F., Kalia, Y. N., Jordan, O. and Borchard, G.
  Int J Pharm. 2018 544 1 297-303 10.1016/j.ijpharm.2018.04.050

• In vitro models for immunogenicity prediction of therapeutic proteins

  Groell, F., Jordan, O. and Borchard, G.
  Eur J Pharm Biopharm. 2018 130 128-142 10.1016/j.ejpb.2018.06.008

• Mapping of drug distribution in the rabbit liver tumor model by complementary fluorescence and mass spectrometry imaging

  Fuchs, K., Kiss, A., Bize, P. E., Duran, R., Denys, A., Hopfgartner, G., Borchard, G. and Jordan, O.
  J Control Release. 2018 269 128-135 10.1016/j.jconrel.2017.10.042

• A robust and easily reproducible protocol for the determination of size and size distribution of iron sucrose using dynamic light scattering

  Di Francesco, T. and Borchard, G.
  J Pharm Biomed Anal. 2018 152 89-93 10.1016/j.jpba.2018.01.029

• Equivalence of glatiramer acetate products: challenges in assessing pharmaceutical equivalence and critical clinical performance attributes

  Borchard, G. and Crommelin, D. J. A.
  Expert Opin Drug Deliv. 2018 15 3 247-259 10.1080/17425247.2018.1418322

2017¶

• Perivascular medical devices and drug delivery systems: Making the right choices

  Mylonaki, I., Allemann, E., Saucy, F., Haefliger, J. A., Delie, F. and Jordan, O.
  Biomaterials. 2017 128 56-68 10.1016/j.biomaterials.2017.02.028

• Association of chitosan and aluminium as a new adjuvant strategy for improved vaccination

  Lebre, F., Bento, D., Ribeiro, J., Colaco, M., Borchard, G., de Lima, M. C. P. and Borges, O.
  Int J Pharm. 2017 527 1-2 103-114 10.1016/j.ijpharm.2017.05.028

• A novel, non-adhesive, precipitating liquid embolic implant with intrinsic radiopacity: feasibility and safety animal study

  Kulcsar, Z., Karol, A., Kronen, P. W., Svende, P., Klein, K., Jordan, O. and Wanke, I.
  Eur Radiol. 2017 27 3 1248-1256 10.1007/s00330-016-4463-7

• Poly--caprolactone/chitosan nanoparticles provide strong adjuvant effect for hepatitis B antigen

  Jesus, S., Soares, E., Borchard, G. and Borges, O.
  Nanomedicine (Lond). 2017 12 19 2335-2348 10.2217/nnm-2017-0138

• Equivalence of complex drug products: advances in and challenges for current regulatory frameworks

  Hussaarts, L., Muhlebach, S., Shah, V. P., McNeil, S., Borchard, G., Fluhmann, B., Weinstein, V., Neervannan, S., Griffiths, E., Jiang, W., Wolff-Holz, E., Crommelin, D. J. A. and de Vlieger, J. S. B.
  Ann N Y Acad Sci. 2017 1407 1 39-49 10.1111/nyas.13347

• Free energy landscape of siRNA-polycation complexation: Elucidating the effect of molecular geometry, polymer flexibility, and charge neutralization

  Grasso, G., Deriu, M. A., Patrulea, V., Borchard, G., Moller, M. and Danani, A.
  PLoS One. 2017 12 10 e0186816 10.1371/journal.pone.0186816

• Drug-eluting embolic microspheres for local drug delivery - State of the art

  Fuchs, K., Duran, R., Denys, A., Bize, P. E., Borchard, G. and Jordan, O.
  J Control Release. 2017 262 127-138 10.1016/j.jconrel.2017.07.016

• Iron sucrose: assessing the similarity between the originator drug and its intended copies

  Di Francesco, T., Philipp, E. and Borchard, G.
  Ann N Y Acad Sci. 2017 1407 1 63-74 10.1111/nyas.13517

2016¶

• Systematic reviews and meta-analyses of benefits and harms of cryotherapy, LEEP, and cold knife conization to treat cervical intraepithelial neoplasia

  Santesso, N., Mustafa, R. A., Wiercioch, W., Kehar, R., Gandhi, S., Chen, Y., Cheung, A., Hopkins, J., Khatib, R., Ma, B., Mustafa, A. A., Lloyd, N., Wu, D., Broutet, N. and Schunemann, H. J.
  Int J Gynaecol Obstet. 2016 132 3 266-71 10.1016/j.ijgo.2015.07.026

• Sustained protein release from hydrogel microparticles using layer-by-layer (LbL) technology

  Sakr, O. S., Jordan, O. and Borchard, G.
  Drug Deliv. 2016 23 8 2747-2755 10.3109/10717544.2015.1069422

• Arming embolic beads with anti-VEGF antibodies and controlling their release using LbL technology

  Sakr, O. S., Berndt, S., Carpentier, G., Cuendet, M., Jordan, O. and Borchard, G.
  J Control Release. 2016 224 199-207 10.1016/j.jconrel.2016.01.010

• Non-covalent modification of granulocyte-colony stimulating factor (G-CSF) by coiled-coil technology

  Reichert, C., Perozzo, R. and Borchard, G.
  Int J Pharm. 2016 511 1 98-103 10.1016/j.ijpharm.2016.06.122

• Noncovalent PEGylation, An Innovative Subchapter in the Field of Protein Modification

  Reichert, C. and Borchard, G.
  J Pharm Sci. 2016 105 2 386-390 10.1002/jps.24692

• Effect of particle size on the biodistribution of nano- and microparticles following intra-articular injection in mice

  Pradal, J., Maudens, P., Gabay, C., Seemayer, C. A., Jordan, O. and Allemann, E.
  Int J Pharm. 2016 498 1-2 119-29 10.1016/j.ijpharm.2015.12.015

• Characterization of pDNA-TMC Nanoparticle Interaction and Stability

  Poecheim, J., Patrulea, V., Reichert, C. and Borchard, G.
  Curr Drug Deliv. 2016 13 3 301-8 10.2174/156720181303160520191305

• Ag85A DNA Vaccine Delivery by Nanoparticles: Influence of the Formulation Characteristics on Immune Responses

  Poecheim, J., Barnier-Quer, C., Collin, N. and Borchard, G.
  Vaccines (Basel). 2016 4 3 10.3390/vaccines4030032

• Peptide-decorated chitosan derivatives enhance fibroblast adhesion and proliferation in wound healing

  Patrulea, V., Hirt-Burri, N., Jeannerat, A., Applegate, L. A., Ostafe, V., Jordan, O. and Borchard, G.
  Carbohydr Polym. 2016 142 114-23 10.1016/j.carbpol.2016.01.045

• Perivascular sustained release of atorvastatin from a hydrogel-microparticle delivery system decreases intimal hyperplasia

  Mylonaki, I., Strano, F., Deglise, S., Allemann, E., Alonso, F., Corpataux, J. M., Dubuis, C., Haefliger, J. A., Jordan, O., Saucy, F. and Delie, F.
  J Control Release. 2016 232 93-102 10.1016/j.jconrel.2016.04.023

• Intranasal Administration of Novel Chitosan Nanoparticle/DNA Complexes Induces Antibody Response to Hepatitis B Surface Antigen in Mice

  Lebre, F., Borchard, G., Faneca, H., Pedroso de Lima, M. C. and Borges, O.
  Mol Pharm. 2016 13 2 472-82 10.1021/acs.molpharmaceut.5b00707

• Immune response elicited by an intranasally delivered HBsAg low-dose adsorbed to poly-epsilon-caprolactone based nanoparticles

  Jesus, S., Soares, E., Costa, J., Borchard, G. and Borges, O.
  Int J Pharm. 2016 504 1-2 59-69 10.1016/j.ijpharm.2016.03.013

• Antitumoral Effect of Sunitinib-eluting Beads in the Rabbit VX2 Tumor Model

  Bize, P., Duran, R., Fuchs, K., Dormond, O., Namur, J., Decosterd, L. A., Jordan, O., Doelker, E. and Denys, A.
  Radiology. 2016 280 2 425-35 10.1148/radiol.2016150361

2015¶

• Establishment and first characterization of a sublingual epithelial and immune cell co-culture model

  Vacher, G., Sublet, E., Gurny, R. and Borchard, G.
  Int J Pharm. 2015 482 1-2 61-7 10.1016/j.ijpharm.2014.11.040

• Controlled drug release from melt-extrudates through processing parameters: a chemometric approach

  Sarraf, A. G., Cherkaoui, S., Jordan, O., Gurny, R. and Doelker, E.
  Int J Pharm. 2015 481 1-2 9-17 10.1016/j.ijpharm.2014.12.046

• Novel Layer-by-Layer Deposition Technique for the Preparation of Double-Chambered Nanoparticle Formulations

  Sakr, O. S., Jordan, O. and Borchard, G.
  J Pharm Sci. 2015 104 8 2637-40 10.1002/jps.24507

• Sustained protein release from hydrogel microparticles using layer-by-layer (LbL) technology

  Sakr, O. S., Jordan, O. and Borchard, G.
  Drug Deliv. 2015 1-9 10.2174/156720181303160520191305

• Intra-articular bioactivity of a p38 MAPK inhibitor and development of an extended-release system

  Pradal, J., Zuluaga, M. F., Maudens, P., Waldburger, J. M., Seemayer, C. A., Doelker, E., Gabay, C., Jordan, O. and Allemann, E.
  Eur J Pharm Biopharm. 2015 93 110-7 10.1016/j.ejpb.2015.03.017

• Nanocarriers for DNA Vaccines: Co-Delivery of TLR-9 and NLR-2 Ligands Leads to Synergistic Enhancement of Proinflammatory Cytokine Release

  Poecheim, J., Heuking, S., Brunner, L., Barnier-Quer, C., Collin, N. and Borchard, G.
  Nanomaterials (Basel). 2015 5 4 2317-2334 10.3390/nano5042317

• Chitosan as a starting material for wound healing applications

  Patrulea, V., Ostafe, V., Borchard, G. and Jordan, O.
  Eur J Pharm Biopharm. 2015 97 Pt B 417-26 10.1016/j.ejpb.2015.08.004

• Optimized synthesis of O-carboxymethyl-N,N,N-trimethyl chitosan

  Patrulea, V., Applegate, L. A., Ostafe, V., Jordan, O. and Borchard, G.
  Carbohydr Polym. 2015 122 46-52 10.1016/j.carbpol.2014.12.014

• Regulatory challenges and approaches to characterize nanomedicines and their follow-on similars

  Muhlebach, S., Borchard, G. and Yildiz, S.
  Nanomedicine (Lond). 2015 10 4 659-74 10.2217/nnm.14.189

• Efficacy study of two novel hyaluronic acid-based formulations for viscosupplementation therapy in an early osteoarthrosic rabbit model

  Kaderli, S., Viguier, E., Watrelot-Virieux, D., Roger, T., Gurny, R., Scapozza, L., Moller, M., Boulocher, C. and Jordan, O.
  Eur J Pharm Biopharm. 2015 96 388-95 10.1016/j.ejpb.2015.09.005

• A novel biocompatible hyaluronic acid-chitosan hybrid hydrogel for osteoarthrosis therapy

  Kaderli, S., Boulocher, C., Pillet, E., Watrelot-Virieux, D., Rougemont, A. L., Roger, T., Viguier, E., Gurny, R., Scapozza, L. and Jordan, O.
  Int J Pharm. 2015 483 1-2 158-68 10.1016/j.ijpharm.2015.01.052

• Sunitinib-eluting beads for chemoembolization: methods for in vitro evaluation of drug release

  Fuchs, K., Bize, P. E., Denys, A., Borchard, G. and Jordan, O.
  Int J Pharm. 2015 482 1-2 68-74 10.1016/j.ijpharm.2014.11.041

2014¶

• Nanomedicines: addressing the scientific and regulatory gap

  Tinkle, S., McNeil, S. E., Muhlebach, S., Bawa, R., Borchard, G., Barenholz, Y. C., Tamarkin, L. and Desai, N.
  Ann N Y Acad Sci. 2014 1313 35-56 10.1111/nyas.12403

• Toll-like receptor 2 regulates the barrier function of human bronchial epithelial monolayers through atypical protein kinase C zeta, and an increase in expression of claudin-1

  Ragupathy, S., Esmaeili, F., Paschoud, S., Sublet, E., Citi, S. and Borchard, G.
  Tissue Barriers. 2014 2 e29166 10.4161/tisb.29166

• Drug-eluting beads loaded with antiangiogenic agents for chemoembolization: in vitro sunitinib loading and release and in vivo pharmacokinetics in an animal model

  Fuchs, K., Bize, P. E., Dormond, O., Denys, A., Doelker, E., Borchard, G. and Jordan, O.
  J Vasc Interv Radiol. 2014 25 3 379-87, 387 e1-2 10.1016/j.jvir.2013.11.039

2013¶

• Recent advances in mucosal immunization using virus-like particles

  Vacher, G., Kaeser, M. D., Moser, C., Gurny, R. and Borchard, G.
  Mol Pharm. 2013 10 5 1596-609 10.1021/mp300597g

• Developing and advancing dry powder inhalation towards enhanced therapeutics

  Stegemann, S., Kopp, S., Borchard, G., Shah, V. P., Senel, S., Dubey, R., Urbanetz, N., Cittero, M., Schoubben, A., Hippchen, C., Cade, D., Fuglsang, A., Morais, J., Borgstrom, L., Farshi, F., Seyfang, K. H., Hermann, R., van de Putte, A., Klebovich, I. and Hincal, A.
  Eur J Pharm Sci. 2013 48 1-2 181-94 10.1016/j.ejps.2012.10.021

• Encapsulation of enzymes in Layer-by-Layer (LbL) structures: latest advances and applications

  Sakr, O. S. and Borchard, G.
  Biomacromolecules. 2013 14 7 2117-35 10.1021/bm400198p

• Multifunctional PLGA-based nanoparticles encapsulating simultaneously hydrophilic antigen and hydrophobic immunomodulator for mucosal immunization

  Primard, C., Poecheim, J., Heuking, S., Sublet, E., Esmaeili, F. and Borchard, G.
  Mol Pharm. 2013 10 8 2996-3004 10.1021/mp400092y

• Fate of TLR-1/TLR-2 agonist functionalised pDNA nanoparticles upon deposition at the human bronchial epithelium in vitro

  Heuking, S., Rothen-Rutishauser, B., Raemy, D. O., Gehr, P. and Borchard, G.
  J Nanobiotechnology. 2013 11 29 10.1186/1477-3155-11-29

• Atorvastatin-loaded hydrogel affects the smooth muscle cells of human veins

  Dubuis, C., May, L., Alonso, F., Luca, L., Mylonaki, I., Meda, P., Delie, F., Jordan, O., Deglise, S., Corpataux, J. M., Saucy, F. and Haefliger, J. A.
  J Pharmacol Exp Ther. 2013 347 3 574-81 10.1124/jpet.113.208769

• Validation of a new 96-well plate spectrophotometric method for the quantification of compound 48/80 associated with particles

  Bento, D., Borchard, G., Goncalves, T. and Borges, O.
  AAPS PharmSciTech. 2013 14 2 649-55 10.1208/s12249-013-9950-4

2012¶

• Noncovalent PEGylation: different effects of dansyl-, L-tryptophan-, phenylbutylamino-, benzyl- and cholesteryl-PEGs on the aggregation of salmon calcitonin and lysozyme

  Mueller, C., Capelle, M. A., Seyrek, E., Martel, S., Carrupt, P. A., Arvinte, T. and Borchard, G.
  J Pharm Sci. 2012 101 6 1995-2008 10.1002/jps.23110

• Toll-like receptor-7 agonist decoration enhances the adjuvanticity of chitosan-DNA nanoparticles

  Heuking, S. and Borchard, G.
  J Pharm Sci. 2012 101 3 1166-77 10.1002/jps.23017

• In vitro evaluation of an RGD-functionalized chitosan derivative for enhanced cell adhesion

  Hansson, A., Hashom, N., Falson, F., Rousselle, P., Jordan, O. and Borchard, G.
  Carbohydr Polym. 2012 90 4 1494-500 10.1016/j.carbpol.2012.07.020

• Preparation and evaluation of nanoparticles for directed tissue engineering

  Hansson, A., Di Francesco, T., Falson, F., Rousselle, P., Jordan, O. and Borchard, G.
  Int J Pharm. 2012 439 1-2 73-80 10.1016/j.ijpharm.2012.09.053

• Preparation and evaluation of nanoparticles for directed tissue engineering

  Hansson, A., Di Francesco, T., Falson, F., Rousselle, P., Jordan, O. and Borchard, G.
  Int J Pharm. 2012 439 1-2 73-80 10.1016/j.ijpharm.2012.09.053

• Dual approach utilizing self microemulsifying technique and novel P-gp inhibitor for effective delivery of taxanes

  Chaurasiya, A., Singh, A. K., Jain, G. K., Warsi, M. H., Sublet, E., Ahmad, F. J., Borchard, G. and Khar, R. K.
  J Microencapsul. 2012 29 6 583-95 10.3109/02652048.2012.668959

• Nanoparticle iron medicinal products - Requirements for approval of intended copies of non-biological complex drugs (NBCD) and the importance of clinical comparative studies

  Borchard, G., Fluhmann, B. and Muhlebach, S.
  Regul Toxicol Pharmacol. 2012 64 2 324-8 10.1016/j.yrtph.2012.08.009

• The School of Pharmacy Geneva-Lausanne (EPGL) - the first ten years

  Borchard, G. and Carrupt, P. A.
  Chimia (Aarau). 2012 66 5 280 10.2533/chimia.2012.280

2011¶

• Lectin mediated biorecognition as a novel strategy for targeted delivery to bladder cancer

  Neutsch, L., Plattner, V. E., Polster-Wildhofen, S., Zidar, A., Chott, A., Borchard, G., Zechner, O., Gabor, F. and Wirth, M.
  J Urol. 2011 186 4 1481-8 10.1016/j.juro.2011.05.040

• Noncovalent pegylation by dansyl-poly(ethylene glycol)s as a new means against aggregation of salmon calcitonin

  Mueller, C., Capelle, M. A., Arvinte, T., Seyrek, E. and Borchard, G.
  J Pharm Sci. 2011 100 5 1648-62 10.1002/jps.22401

• Tryptophan-mPEGs: novel excipients that stabilize salmon calcitonin against aggregation by non-covalent PEGylation

  Mueller, C., Capelle, M. A., Arvinte, T., Seyrek, E. and Borchard, G.
  Eur J Pharm Biopharm. 2011 79 3 646-57 10.1016/j.ejpb.2011.06.003

• Inhaled drug therapy for treatment of tuberculosis

  Misra, A., Hickey, A. J., Rossi, C., Borchard, G., Terada, H., Makino, K., Fourie, P. B. and Colombo, P.
  Tuberculosis (Edinb). 2011 91 1 71-81 10.1016/j.tube.2010.08.009

• Injectable rhBMP-2-loaded chitosan hydrogel composite: osteoinduction at ectopic site and in segmental long bone defect

  Luca, L., Rougemont, A. L., Walpoth, B. H., Boure, L., Tami, A., Anderson, J. M., Jordan, O. and Gurny, R.
  J Biomed Mater Res A. 2011 96 1 66-74 10.1002/jbm.a.32957

• Progress towards a needle-free hepatitis B vaccine

  Lebre, F., Borchard, G., de Lima, M. C. and Borges, O.
  Pharm Res. 2011 28 5 986-1012 10.1007/s11095-010-0314-4

2010¶

• The effects of carrier nature and pH on rhBMP-2-induced ectopic bone formation

  Luca, L., Rougemont, A. L., Walpoth, B. H., Gurny, R. and Jordan, O.
  J Control Release. 2010 147 1 38-44 10.1016/j.jconrel.2010.06.011

• Physical instability, aggregation and conformational changes of recombinant human bone morphogenetic protein-2 (rhBMP-2)

  Luca, L., Capelle, M. A., Machaidze, G., Arvinte, T., Jordan, O. and Gurny, R.
  Int J Pharm. 2010 391 1-2 48-54 10.1016/j.ijpharm.2010.02.015

• The in vivo performance of magnetic particle-loaded injectable, in situ gelling, carriers for the delivery of local hyperthermia

  Le Renard, P. E., Jordan, O., Faes, A., Petri-Fink, A., Hofmann, H., Rufenacht, D., Bosman, F., Buchegger, F. and Doelker, E.
  Biomaterials. 2010 31 4 691-705 10.1016/j.biomaterials.2009.09.091

• Comparative study of chemoembolization loadable beads: in vitro drug release and physical properties of DC bead and hepasphere loaded with doxorubicin and irinotecan

  Jordan, O., Denys, A., De Baere, T., Boulens, N. and Doelker, E.
  J Vasc Interv Radiol. 2010 21 7 1084-90 10.1016/j.jvir.2010.02.042

• Mucosal vaccines: recent progress in understanding the natural barriers

  Borges, O., Lebre, F., Bento, D., Borchard, G. and Junginger, H. E.
  Pharm Res. 2010 27 2 211-23 10.1007/s11095-009-0011-3

• Nanomedicine and immunotherapy

  Borchard, G.
  Expert Rev Vaccines. 2010 9 11 1245-6 10.1586/erv.10.128

2009¶

• Gender-specific differences between the concentrations of nonvolatile (R)/(S)-3-methyl-3-sulfanylhexan-1-Ol and (R)/(S)-3-hydroxy-3-methyl-hexanoic acid odor precursors in axillary secretions

  Troccaz, M., Borchard, G., Vuilleumier, C., Raviot-Derrien, S., Niclass, Y., Beccucci, S. and Starkenmann, C.
  Chem Senses. 2009 34 3 203-10 10.1093/chemse/bjn076

• Novel thermosensitive chitosan hydrogels: in vivo evaluation

  Patois, E., Osorio-da Cruz, S., Tille, J. C., Walpoth, B., Gurny, R. and Jordan, O.
  J Biomed Mater Res A. 2009 91 2 324-30 10.1002/jbm.a.32211

• Local moderate magnetically induced hyperthermia using an implant formed in situ in a mouse tumor model

  Le Renard, P. E., Buchegger, F., Petri-Fink, A., Bosman, F., Rufenacht, D., Hofmann, H., Doelker, E. and Jordan, O.
  Int J Hyperthermia. 2009 25 3 229-39 10.1080/02656730802713557

• Toll-like receptor-2 agonist functionalized biopolymer for mucosal vaccination

  Heuking, S., Iannitelli, A., Di Stefano, A. and Borchard, G.
  Int J Pharm. 2009 381 2 97-105 10.1016/j.ijpharm.2009.03.039

• Stimulation of human macrophages (THP-1) using Toll-like receptor-2 (TLR-2) agonist decorated nanocarriers

  Heuking, S., Adam-Malpel, S., Sublet, E., Iannitelli, A., Stefano, Ad and Borchard, G.
  J Drug Target. 2009 17 8 662-70 10.1080/10611860903106034

• Magnetically retainable microparticles for drug delivery to the joint: efficacy studies in an antigen-induced arthritis model in mice

  Butoescu, N., Seemayer, C. A., Palmer, G., Guerne, P. A., Gabay, C., Doelker, E. and Jordan, O.
  Arthritis Res Ther. 2009 11 3 R72 10.1186/ar2701

• Dexamethasone-containing PLGA superparamagnetic microparticles as carriers for the local treatment of arthritis

  Butoescu, N., Seemayer, C. A., Foti, M., Jordan, O. and Doelker, E.
  Biomaterials. 2009 30 9 1772-80 10.1016/j.biomaterials.2008.12.017

• Intra-articular drug delivery systems for the treatment of rheumatic diseases: a review of the factors influencing their performance

  Butoescu, N., Jordan, O. and Doelker, E.
  Eur J Pharm Biopharm. 2009 73 2 205-18 10.1016/j.ejpb.2009.06.009

• Dexamethasone-containing biodegradable superparamagnetic microparticles for intra-articular administration: physicochemical and magnetic properties, in vitro and in vivo drug release

  Butoescu, N., Jordan, O., Burdet, P., Stadelmann, P., Petri-Fink, A., Hofmann, H. and Doelker, E.
  Eur J Pharm Biopharm. 2009 72 3 529-38 10.1016/j.ejpb.2009.03.003

• Pulmonary delivery of DNA encoding Mycobacterium tuberculosis latency antigen Rv1733c associated to PLGA-PEI nanoparticles enhances T cell responses in a DNA prime/protein boost vaccination regimen in mice

  Bivas-Benita, M., Lin, M. Y., Bal, S. M., van Meijgaarden, K. E., Franken, K. L., Friggen, A. H., Junginger, H. E., Borchard, G., Klein, M. R. and Ottenhoff, T. H.
  Vaccine. 2009 27 30 4010-7 10.1016/j.vaccine.2009.04.033

2008¶

• Properties of recombinant Staphylococcus haemolyticus cystathionine beta-lyase (metC) and its potential role in the generation of volatile thiols in axillary malodor

  Troccaz, M., Benattia, F., Borchard, G. and Clark, A. J.
  Chem Biodivers. 2008 5 11 2372-85 10.1002/cbdv.200890202

• A novel thermoresponsive hydrogel based on chitosan

  Schuetz, Y. B., Gurny, R. and Jordan, O.
  Eur J Pharm Biopharm. 2008 68 1 19-25 10.1016/j.ejpb.2007.06.020

• Co-encapsulation of dexamethasone 21-acetate and SPIONs into biodegradable polymeric microparticles designed for intra-articular delivery

  Butoescu, N., Jordan, O., Petri-Fink, A., Hofmann, H. and Doelker, E.
  J Microencapsul. 2008 25 5 339-50 10.1080/02652040801999551

• Alginate coated chitosan nanoparticles are an effective subcutaneous adjuvant for hepatitis B surface antigen

  Borges, O., Silva, M., de Sousa, A., Borchard, G., Junginger, H. E. and Cordeiro-da-Silva, A.
  Int Immunopharmacol. 2008 8 13-14 1773-80 10.1016/j.intimp.2008.08.013

• Immune response by nasal delivery of hepatitis B surface antigen and codelivery of a CpG ODN in alginate coated chitosan nanoparticles

  Borges, O., Cordeiro-da-Silva, A., Tavares, J., Santarem, N., de Sousa, A., Borchard, G. and Junginger, H. E.
  Eur J Pharm Biopharm. 2008 69 2 405-16 10.1016/j.ejpb.2008.01.019

2007¶

• Delivery of G3139 using releasable PEG-linkers: impact on pharmacokinetic profile and anti-tumor efficacy

  Zhao, H., Peng, P., Longley, C., Zhang, Y., Borowski, V., Mehlig, M., Reddy, P., Xia, J., Borchard, G., Lipman, J., Benimetskaya, L. and Stein, C. A.
  J Control Release. 2007 119 2 143-52 10.1016/j.jconrel.2006.12.021

• Clinical evaluation of bioadhesive hydrogels for topical delivery of hexylaminolevulinate to Barrett's esophagus

  Collaud, S., Warloe, T., Jordan, O., Gurny, R. and Lange, N.
  J Control Release. 2007 123 3 203-10 10.1016/j.jconrel.2007.08.015

• Evaluation of the immune response following a short oral vaccination schedule with hepatitis B antigen encapsulated into alginate-coated chitosan nanoparticles

  Borges, O., Tavares, J., de Sousa, A., Borchard, G., Junginger, H. E. and Cordeiro-da-Silva, A.
  Eur J Pharm Sci. 2007 32 4-5 278-90 10.1016/j.ejps.2007.08.005

• Induction of lymphocytes activated marker CD69 following exposure to chitosan and alginate biopolymers

  Borges, O., Borchard, G., de Sousa, A., Junginger, H. E. and Cordeiro-da-Silva, A.
  Int J Pharm. 2007 337 1-2 254-64 10.1016/j.ijpharm.2007.01.021

2006¶

• Enhancement of bronchial octreotide absorption by chitosan and N-trimethyl chitosan shows linear in vitro/in vivo correlation

  Florea, B. I., Thanou, M., Junginger, H. E. and Borchard, G.
  J Control Release. 2006 110 2 353-61 10.1016/j.jconrel.2005.10.001

• Uptake studies in rat Peyer's patches, cytotoxicity and release studies of alginate coated chitosan nanoparticles for mucosal vaccination

  Borges, O., Cordeiro-da-Silva, A., Romeijn, S. G., Amidi, M., de Sousa, A., Borchard, G. and Junginger, H. E.
  J Control Release. 2006 114 3 348-58 10.1016/j.jconrel.2006.06.011

• Preparation and characterization of protein-loaded N-trimethyl chitosan nanoparticles as nasal delivery system

  Amidi, M., Romeijn, S. G., Borchard, G., Junginger, H. E., Hennink, W. E. and Jiskoot, W.
  J Control Release. 2006 111 1-2 107-16 10.1016/j.jconrel.2005.11.014

2005¶

• Antitumor activity of poly(ethylene glycol)-camptothecin conjugate: the inhibition of tumor growth in vivo

  Yu, D., Peng, P., Dharap, S. S., Wang, Y., Mehlig, M., Chandna, P., Zhao, H., Filpula, D., Yang, K., Borowski, V., Borchard, G., Zhang, Z. and Minko, T.
  J Control Release. 2005 110 1 90-102 10.1016/j.jconrel.2005.09.050

• Biomaterials used in injectable implants (liquid embolics) for percutaneous filling of vascular spaces

  Jordan, O., Doelker, E. and Rufenacht, D. A.
  Cardiovasc Intervent Radiol. 2005 28 5 561-9 10.1007/s00270-004-0238-7

• Preparation and characterization of chitosan and trimethyl-chitosan-modified poly-(epsilon-caprolactone) nanoparticles as DNA carriers

  Haas, J., Ravi Kumar, M. N., Borchard, G., Bakowsky, U. and Lehr, C. M.
  AAPS PharmSciTech. 2005 6 1 E22-30 10.1208/pt060106

• Preparation of coated nanoparticles for a new mucosal vaccine delivery system

  Borges, O., Borchard, G., Verhoef, J. C., de Sousa, A. and Junginger, H. E.
  Int J Pharm. 2005 299 1-2 155-66 10.1016/j.ijpharm.2005.04.037

• Non-invasive pulmonary aerosol delivery in mice by the endotracheal route

  Bivas-Benita, M., Zwier, R., Junginger, H. E. and Borchard, G.
  Eur J Pharm Biopharm. 2005 61 3 214-8 10.1016/j.ejpb.2005.04.009

• Pulmonary DNA vaccination: concepts, possibilities and perspectives

  Bivas-Benita, M., Ottenhoff, T. H., Junginger, H. E. and Borchard, G.
  J Control Release. 2005 107 1 1-29 10.1016/j.jconrel.2005.05.028

2004¶

• In vitro evaluation of intestinal absorption of desmopressin using drug-delivery systems based on superporous hydrogels

  Polnok, A., Verhoef, J. C., Borchard, G., Sarisuta, N. and Junginger, H. E.
  Int J Pharm. 2004 269 2 303-10 10.1016/j.ijpharm.2003.09.022

• Influence of methylation process on the degree of quaternization of N-trimethyl chitosan chloride

  Polnok, A., Borchard, G., Verhoef, J. C., Sarisuta, N. and Junginger, H. E.
  Eur J Pharm Biopharm. 2004 57 1 77-83 10.1016/S0939-6411(03)00151-6

• Novel injectable urethral bulking agents for the treatment of urinary incontinence

  Jordan, O., Doelker, E., Defabiani, N., Caviezel, A. and Iselin, C.
  J Mater Sci Mater Med. 2004 15 4 519-22 10.1023/B:JMSM.0000021131.15283.18

• Feasibility study on the retention of superporous hydrogel composite polymer in the intestinal tract of man using scintigraphy

  Dorkoosh, F. A., Stokkel, M. P., Blok, D., Borchard, G., Rafiee-Tehrani, M., Verhoef, J. C. and Junginger, H. E.
  J Control Release. 2004 99 2 199-206 10.1016/j.jconrel.2004.06.012

• Transport of octreotide and evaluation of mechanism of opening the paracellular tight junctions using superporous hydrogel polymers in Caco-2 cell monolayers

  Dorkoosh, F. A., Broekhuizen, C. A., Borchard, G., Rafiee-Tehrani, M., Verhoef, J. C. and Junginger, H. E.
  J Pharm Sci. 2004 93 3 743-52 10.1002/jps.10570

• Pulmonary delivery of chitosan-DNA nanoparticles enhances the immunogenicity of a DNA vaccine encoding HLA-A*0201-restricted T-cell epitopes of Mycobacterium tuberculosis

  Bivas-Benita, M., van Meijgaarden, K. E., Franken, K. L., Junginger, H. E., Borchard, G., Ottenhoff, T. H. and Geluk, A.
  Vaccine. 2004 22 13-14 1609-15 10.1016/j.vaccine.2003.09.044

• PLGA-PEI nanoparticles for gene delivery to pulmonary epithelium

  Bivas-Benita, M., Romeijn, S., Junginger, H. E. and Borchard, G.
  Eur J Pharm Biopharm. 2004 58 1 1-6 10.1016/j.ejpb.2004.03.008

• Cationic submicron emulsions for pulmonary DNA immunization

  Bivas-Benita, M., Oudshoorn, M., Romeijn, S., van Meijgaarden, K., Koerten, H., van der Meulen, H., Lambert, G., Ottenhoff, T., Benita, S., Junginger, H. and Borchard, G.
  J Control Release. 2004 100 1 145-55 10.1016/j.jconrel.2004.08.008

2003¶

• Identification of an internalising peptide in differentiated Calu-3 cells by phage display technology; application to gene delivery to the airways

  Florea, B. I., Molenaar, T. J., Bot, I., Michon, I. N., Kuiper, J., Van Berkel, T. J., Junginger, H. E., Biessen, E. A. and Borchard, G.
  J Drug Target. 2003 11 7 383-90 10.1080/10611860310001642389

• Drug transport and metabolism characteristics of the human airway epithelial cell line Calu-3

  Florea, B. I., Cassara, M. L., Junginger, H. E. and Borchard, G.
  J Control Release. 2003 87 1-3 131-8 10.1016/S0168-3659(02)00356-5

• Generation of Toxoplasma gondii GRA1 protein and DNA vaccine loaded chitosan particles: preparation, characterization, and preliminary in vivo studies

  Bivas-Benita, M., Laloup, M., Versteyhe, S., Dewit, J., De Braekeleer, J., Jongert, E. and Borchard, G.
  Int J Pharm. 2003 266 1-2 17-27 10.1016/S0378-5173(03)00377-6

2002¶

• Transport of chitosan microparticles for mucosal vaccine delivery in a human intestinal M-cell model

  van der Lubben, I. M., van Opdorp, F. A., Hengeveld, M. R., Onderwater, J. J., Koerten, H. K., Verhoef, J. C., Borchard, G. and Junginger, H. E.
  J Drug Target. 2002 10 6 449-56 10.1080/1061186021000038319

• Quaternized chitosan oligomers as novel gene delivery vectors in epithelial cell lines

  Thanou, M., Florea, B. I., Geldof, M., Junginger, H. E. and Borchard, G.
  Biomaterials. 2002 23 1 153-9

• Transfection efficiency and toxicity of polyethylenimine in differentiated Calu-3 and nondifferentiated COS-1 cell cultures

  Florea, B. I., Meaney, C., Junginger, H. E. and Borchard, G.
  AAPS PharmSci. 2002 4 3 E12 10.1208/ps040312

• Peroral absorption of octreotide in pigs formulated in delivery systems on the basis of superporous hydrogel polymers

  Dorkoosh, F. A., Verhoef, J. C., Verheijden, J. H., Rafiee-Tehrani, M., Borchard, G. and Junginger, H. E.
  Pharm Res. 2002 19 10 1532-6

• Intestinal absorption of human insulin in pigs using delivery systems based on superporous hydrogel polymers

  Dorkoosh, F. A., Verhoef, J. C., Borchard, G., Rafiee-Tehrani, M., Verheijden, J. H. and Junginger, H. E.
  Int J Pharm. 2002 247 1-2 47-55

• Effects of superporous hydrogels on paracellular drug permeability and cytotoxicity studies in Caco-2 cell monolayers

  Dorkoosh, F. A., Setyaningsih, D., Borchard, G., Rafiee-Tehrani, M., Verhoef, J. C. and Junginger, H. E.
  Int J Pharm. 2002 241 1 35-45

• Peroral delivery systems based on superporous hydrogel polymers: release characteristics for the peptide drugs buserelin, octreotide and insulin

  Dorkoosh, F. A., Coos Verhoef, J., Ambagts, M. H., Rafiee-Tehrani, M., Borchard, G. and Junginger, H. E.
  Eur J Pharm Sci. 2002 15 5 433-9

• Evaluation of superporous hydrogel (SPH) and SPH composite in porcine intestine ex-vivo: assessment of drug transport, morphology effect, and mechanical fixation to intestinal wall

  Dorkoosh, F. A., Borchard, G., Rafiee-Tehrani, M., Verhoef, J. C. and Junginger, H. E.
  Eur J Pharm Biopharm. 2002 53 2 161-6

• Transport and local metabolism of budesonide and fluticasone propionate in a human bronchial epithelial cell line (Calu-3)

  Borchard, G., Cassara, M. L., Roemele, P. E., Florea, B. I. and Junginger, H. E.
  J Pharm Sci. 2002 91 6 1561-7 10.1002/jps.10151

2001¶

• Chitosan microparticles for oral vaccination: preparation, characterization and preliminary in vivo uptake studies in murine Peyer's patches

  van der Lubben, I. M., Verhoef, J. C., van Aelst, A. C., Borchard, G. and Junginger, H. E.
  Biomaterials. 2001 22 7 687-94

• Chitosan and its derivatives in mucosal drug and vaccine delivery

  van der Lubben, I. M., Verhoef, J. C., Borchard, G. and Junginger, H. E.
  Eur J Pharm Sci. 2001 14 3 201-7

• Chitosan for mucosal vaccination

  van der Lubben, I. M., Verhoef, J. C., Borchard, G. and Junginger, H. E.
  Adv Drug Deliv Rev. 2001 52 2 139-44

• In vivo uptake of chitosan microparticles by murine Peyer's patches: visualization studies using confocal laser scanning microscopy and immunohistochemistry

  Van Der Lubben, I. M., Konings, F. A., Borchard, G., Verhoef, J. C. and Junginger, H. E.
  J Drug Target. 2001 9 1 39-47

• Development of a new aerosol delivery system for systemic pulmonary delivery in anaesthetized and orotracheal intubated rats

  Lizio, R., Marx, D., Nolte, T., Lehr, C. M., Sarlikiotis, A. W., Borchard, G., Jahn, W. and Klenner, T.
  Lab Anim. 2001 35 3 261-70 10.1258/0023677011911589

• Systemic delivery of cetrorelix to rats by a new aerosol delivery system

  Lizio, R., Klenner, T., Sarlikiotis, A. W., Romeis, P., Marx, D., Nolte, T., Jahn, W., Borchard, G. and Lehr, C. M.
  Pharm Res. 2001 18 6 771-9

• Evidence of P-glycoprotein mediated apical to basolateral transport of flunisolide in human broncho-tracheal epithelial cells (Calu-3)

  Florea, B. I., van der Sandt, I. C., Schrier, S. M., Kooiman, K., Deryckere, K., de Boer, A. G., Junginger, H. E. and Borchard, G.
  Br J Pharmacol. 2001 134 7 1555-63 10.1038/sj.bjp.0704390

• Development and characterization of a novel peroral peptide drug delivery system

  Dorkoosh, F. A., Verhoef, J. C., Borchard, G., Rafiee-Tehrani, M. and Junginger, H. E.
  J Control Release. 2001 71 3 307-18

• Lectin-functionalized liposomes for pulmonary drug delivery: interaction with human alveolar epithelial cells

  Bruck, A., Abu-Dahab, R., Borchard, G., Schafer, U. F. and Lehr, C. M.
  J Drug Target. 2001 9 4 241-51

• Modern drug delivery applications of chitosan

  Borchard, G. and Junginger, H. E.
  Adv Drug Deliv Rev. 2001 52 2 103

• Chitosans for gene delivery

  Borchard, G.
  Adv Drug Deliv Rev. 2001 52 2 145-50

2000¶

• Systemic delivery of the GnRH antagonist cetrorelix by intratracheal instillation in anesthetized rats

  Lizio, R., Klenner, T., Borchard, G., Romeis, P., Sarlikiotis, A. W., Reissmann, T. and Lehr, C. M.
  Eur J Pharm Sci. 2000 9 3 253-8

• Preparation and NMR characterization of superporous hydrogels and SPH composites

  Dorkoosh, F.A., Brussee, J., Verhoef, J.C., Borchard, G., Rafiee-Tehrani, M. and Junginger, H.E.
  Polymer 41 2000 8213-8220

• Chitosan microparticles for oral vaccination: optimization and characterization

  van der Lubben, I.M., Konings, F.A.J., Borchard, G., Verhoef, J.C. and Junginger, H.E.
  Adv. Chitin Sci. 4 2000 250-253

1998¶

• Effects of electrical current on the permeability of epithelial cell monolayers.

  Schaffnit,R., Wicklandt, P., Borchard, G. and Moll, F.
  Pharm. Pharmacol. Lett. 8 1998 140-143

• Absorption enhancement by lectin-mediated endo- and transcytosis

  Haltner, E., Borchard, G. and Lehr, C. M.
  Methods Mol Med. 1998 9 567-81 10.1385/0-89603-396-1:567

• Transport of proteolytic enzymes across Caco-2 cell monolayers

  Bock, U., Kolac, C., Borchard, G., Koch, K., Fuchs, R., Streichhan, P. and Lehr, C. M.
  Pharm Res. 1998 15 9 1393-400

1996¶

• The potential of mucoadhesive polymers in enhancing intestinal peptide drug absorption. III: Effects of chitosan-glutamate and carbomer on epithelial tight junctions in vitro.

  Borchard, G., Luessen, H.L., de Boer, A.G., Verhoef, J.C., Lehr, C.-M. and Junginger, H.E.

• The role of serum complement on the organ distribution of intravenously administered poly (methyl methacrylate) nanoparticles: effects of pre-coating with plasma and with serum complement

  Borchard, G. and Kreuter, J.
  Pharm Res. 1996 13 7 1055-8 10.1023/A:1011949521144

1995¶

• Radiolabeled 75Se-silica nanoparticles: synthesis, characterization and coating with w-functionalized alkylsilane surfactants.

  Brandriss, S., Borchard, G., Kreuter, J. and Margel, S.
  Reactive Polymers 25 1995 111-125

• Mucoadhesive polymers in peroral peptide drug delivery. II. Carbomer and polycarbophil are potent inhibitors of the intestinal proteolytic enzyme trypsin

  Luessen, H. L., Verhoef, J. C., Borchard, G., Lehr, C. M., de Boer, A. G. and Junginger, H. E.
  Pharm Res. 1995 12 9 1293-8

1994¶

• Body distribution of 75Se-radiolabeled silica nanoparticles covalently coated with w-functionalized surfactants after intravenous injection in rats.

  Borchard, G. Brandriss, S., Margel, S.and Kreuter, J.
  J. Drug Target. 2 1994 61 - 77

• Uptake of surfactant-coated poly(methyl methacrylate)-nanoparticles by bovine brain microvessel endothelial cell monolayers.

  Borchard, G., Audus, K.L. , Shi, F. and Kreuter, J.
  Int. J. Pharm. 110 1994 29-35

1993¶

• Interaction of serum components with poly(methylmethacrylate) nanoparticles and the resulting body distribution after intravenous injection in rats

  Borchard, G. and Kreuter, J.
  J Drug Target. 1993 1 1 15-9 10.3109/10611869308998760